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KMID : 0438420140210030163
Korean Journal of Bone Metabolism
2014 Volume.21 No. 3 p.163 ~ p.167
Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts
Ikeda Kyoji

Takeshita Sunao
Abstract
Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues. Among multiple phases of the complex remodeling process, we focus in this review on factors and mechanisms that are involved in the coupling of bone formation to preceding resorption.
KEYWORD
Bone remodeling, Bone resorption, Osteoblasts, Osteoclasts
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